Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop
by Engineering, and Medicine National Academies of Sciences, Health and Medicine Division, Board on Health Sciences Policy, Forum on Neuroscience and Nervous System Disorders
English | June 15, 2017 | ASIN: B071GVP5LF | 95 Pages | PDF | 2 MB
Compared with other disease areas, central nervous system (CNS) disorders have had the highest failure rate for new compounds in advanced clinical trials. Most CNS drugs fail because of efficacy, and the core issue underlying these problems is a poor understanding of disease biology.